Chromatin organization revealed by nanostructure of irradiation induced γH2AX, 53BP1 and Rad51 foci

The spatial distribution of DSB repair factors γH2AX, 53BP1 and Rad51 in ionizing radiation induced foci (IRIF) in HeLa cells using super resolution STED nanoscopy after low and high linear energy transfer (LET) irradiation was investigated. 53BP1 and γH2AX form IRIF with same mean size of (540 ± 40...

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Publicado no:Sci Rep
Main Authors: Reindl, Judith, Girst, Stefanie, Walsh, Dietrich W. M., Greubel, Christoph, Schwarz, Benjamin, Siebenwirth, Christian, Drexler, Guido A., Friedl, Anna A., Dollinger, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240115/
https://ncbi.nlm.nih.gov/pubmed/28094292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40616
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