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Nucleolar TRF2 attenuated nucleolus stress-induced HCC cell-cycle arrest by altering rRNA synthesis

The nucleolus is an important organelle that is responsible for the biogenesis of ribosome RNA (rRNA) and ribosomal subunits assembly. It is also deemed to be the center of metabolic control, considering the critical role of ribosomes in protein translation. Perturbations of rRNA synthesis are close...

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Pubblicato in:Cell Death Dis
Autori principali: Yuan, Fuwen, Xu, Chenzhong, Li, Guodong, Tong, Tanjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938709/
https://ncbi.nlm.nih.gov/pubmed/29725012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0572-3
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