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Synergistic action of RNA polymerases in overcoming the nucleosomal barrier

During gene expression, RNA polymerase (RNAP) encounters a major barrier at a nucleosome and yet must access the nucleosomal DNA. In vivo evidence suggests that multiple RNAPs might increase transcription efficiency through nucleosomes. Here we have quantitatively investigated this hypothesis using...

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Hlavní autoři: Jin, Jing, Bai, Lu, Johnson, Daniel S., Fulbright, Robert M., Kireeva, Maria L., Kashlev, Mikhail, Wang, Michelle D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938954/
https://ncbi.nlm.nih.gov/pubmed/20453861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1798
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