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Synergistic action of RNA polymerases in overcoming the nucleosomal barrier
During gene expression, RNA polymerase (RNAP) encounters a major barrier at a nucleosome and yet must access the nucleosomal DNA. In vivo evidence suggests that multiple RNAPs might increase transcription efficiency through nucleosomes. Here we have quantitatively investigated this hypothesis using...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938954/ https://ncbi.nlm.nih.gov/pubmed/20453861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1798 |
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