Llwytho...

Nucleosomal Fluctuations Govern the Transcription Dynamics of RNA Polymerase II

RNA polymerase II (Pol II) must overcome the barriers imposed by nucleosomes during transcription elongation. We have developed an optical tweezers assay to follow individual Pol II complexes as they transcribe nucleosomal DNA. Our results indicate that the nucleosome behaves as a fluctuating barrie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hodges, Courtney, Bintu, Lacramioara, Lubkowska, Lucyna, Kashlev, Mikhail, Bustamante, Carlos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775800/
https://ncbi.nlm.nih.gov/pubmed/19644123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1172926
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