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Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism
During transcription elongation, RNA polymerase has been assumed to attain equilibrium between pre- and post-translocated states rapidly relative to the subsequent catalysis. Under this assumption, recent single-molecule studies proposed a branched Brownian ratchet mechanism that necessitates a puta...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778554/ https://ncbi.nlm.nih.gov/pubmed/24066225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00971 |
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