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The Role of Pyrophosphorolysis in the Initiation-to-Elongation Transition by E. coli RNA Polymerase
RNA polymerase can cleave a phosphodiester bond at the 3′ end of a nascent RNA in the presence of pyrophosphate producing NTP. Pyrophosphorolysis has been characterized during elongation steps of transcription where its rate is significantly slower than the forward rate of NMP addition. In contrast,...
Shranjeno v:
| izdano v: | J Mol Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8190572/ https://ncbi.nlm.nih.gov/pubmed/31029704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.04.020 |
| Oznake: |
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