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The Role of Pyrophosphorolysis in the Initiation-to-Elongation Transition by E. coli RNA Polymerase

RNA polymerase can cleave a phosphodiester bond at the 3′ end of a nascent RNA in the presence of pyrophosphate producing NTP. Pyrophosphorolysis has been characterized during elongation steps of transcription where its rate is significantly slower than the forward rate of NMP addition. In contrast,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Biol
Prif Awduron: Imashimizu, Masahiko, Kireeva, Maria L., Lubkowska, Lucyna, Kashlev, Mikhail, Shimamoto, Nobuo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190572/
https://ncbi.nlm.nih.gov/pubmed/31029704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.04.020
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