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Direct assessment of transcription fidelity by high-resolution RNA sequencing

Cancerous and aging cells have long been thought to be impacted by transcription errors that cause genetic and epigenetic changes. Until now, a lack of methodology for directly assessing such errors hindered evaluation of their impact to the cells. We report a high-resolution Illumina RNA-seq method...

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Bibliografiske detaljer
Main Authors: Imashimizu, Masahiko, Oshima, Taku, Lubkowska, Lucyna, Kashlev, Mikhail
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799451/
https://ncbi.nlm.nih.gov/pubmed/23925128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt698
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