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The Role of Pyrophosphorolysis in the Initiation-to-Elongation Transition by E. coli RNA Polymerase

RNA polymerase can cleave a phosphodiester bond at the 3′ end of a nascent RNA in the presence of pyrophosphate producing NTP. Pyrophosphorolysis has been characterized during elongation steps of transcription where its rate is significantly slower than the forward rate of NMP addition. In contrast,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Mol Biol
Päätekijät: Imashimizu, Masahiko, Kireeva, Maria L., Lubkowska, Lucyna, Kashlev, Mikhail, Shimamoto, Nobuo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190572/
https://ncbi.nlm.nih.gov/pubmed/31029704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.04.020
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