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Intrinsic Translocation Barrier as an Initial Step in Pausing by RNA Polymerase II
Pausing of RNA polymerase II (RNAP II) by backtracking on the DNA is a major regulatory mechanism in control of eukaryotic transcription. Backtracking occurs by extrusion of the 3’ end of the RNA from the active center after bond formation and before translocation of RNAP II on DNA. In several docum...
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| Izdano u: | J Mol Biol |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7649676/ https://ncbi.nlm.nih.gov/pubmed/23238253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.12.002 |
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