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Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo
BACKGROUND: Transcription elongation is frequently interrupted by pausing signals in DNA, with downstream effects on gene expression. Transcription errors also induce prolonged pausing, which can lead to a destabilized genome by interfering with DNA replication. Mechanisms of pausing associated with...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457086/ https://ncbi.nlm.nih.gov/pubmed/25976475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0666-5 |
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