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Nucleosomal Elements That Control the Topography of the Barrier to Transcription

The nucleosome represents a mechanical barrier to transcription that operates as a general regulator of gene expression. We investigate how each nucleosomal component – the histone tails, the specific histone-DNA contacts, and the DNA sequence – contributes to the strength of the barrier. Removal of...

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Autores principales: Bintu, Lacramioara, Ishibashi, Toyotaka, Dangkulwanich, Manchuta, Wu, Yueh-Yi, Lubkowska, Lucyna, Kashlev, Mikhail, Bustamante, Carlos
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508686/
https://ncbi.nlm.nih.gov/pubmed/23141536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.009
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