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Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats

Trinucleotide repeats can form stable secondary structures that promote genomic instability. To determine how such structures are resolved, we have defined biochemical activities of the related RAD2 family nucleases, FEN1 (Flap endonuclease 1) and EXO1 (exonuclease 1), on substrates that recapitulat...

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Bibliografski detalji
Glavni autori: Vallur, Aarthy C., Maizels, Nancy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937877/
https://ncbi.nlm.nih.gov/pubmed/20643645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132738
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