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Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA
BACKGROUND: Exonuclease 1 (EXO1) and Flap endonuclease 1 (FEN1) are members of the RAD2 family of structure-specific nucleases. Genetic analysis has identified roles for EXO1 and FEN1 in replication, recombination, DNA repair and maintenance of telomeres. Telomeres are composed of G-rich repeats tha...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811187/ https://ncbi.nlm.nih.gov/pubmed/20126648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008908 |
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