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Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regions
Eukaryotic exonuclease 1 functions in replication, recombination, mismatch repair, telomere maintenance, immunoglobulin (Ig) gene class switch recombination, and somatic hypermutation. The enzyme has 5′–3′ exonuclease, flap endonuclease, and weak RNaseH activity in vitro, but it has been difficult t...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575450/ https://ncbi.nlm.nih.gov/pubmed/18940926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805327105 |
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