Type I Phosphatidylinositol Phosphate Kinase Beta Regulates Focal Adhesion Disassembly by Promoting β1 Integrin Endocytosis

Cell migration requires the regulated disassembly of focal adhesions, but the underlying mechanisms remain poorly defined. We have previously shown that focal adhesion disassembly requires the dynamin 2- and clathrin-dependent endocytosis of ligand-activated β1 integrins. Here, we identify type I ph...

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Main Authors: Chao, Wei-Ting, Ashcroft, Felicity, Daquinag, Alexes C., Vadakkan, Tegy, Wei, Zhubo, Zhang, Pumin, Dickinson, Mary E., Kunz, Jeannette
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937533/
https://ncbi.nlm.nih.gov/pubmed/20624912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01207-09
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