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Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation
Phosphatidylinositol-4,5-bisphosphate (PI4,5P(2)) is a critical regulator of cell migration, but the roles of the type I phosphatidylinositol-4-phosphate 5-kinases (PIPKIs), which synthesize PI4,5P(2), have yet to be fully defined in this process. In this study, we report that one kinase, PIPKI-α, i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930278/ https://ncbi.nlm.nih.gov/pubmed/20660631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911110 |
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