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Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation

Phosphatidylinositol-4,5-bisphosphate (PI4,5P(2)) is a critical regulator of cell migration, but the roles of the type I phosphatidylinositol-4-phosphate 5-kinases (PIPKIs), which synthesize PI4,5P(2), have yet to be fully defined in this process. In this study, we report that one kinase, PIPKI-α, i...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Chao, Wei-Ting, Daquinag, Alexes C., Ashcroft, Felicity, Kunz, Jeannette
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930278/
https://ncbi.nlm.nih.gov/pubmed/20660631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911110
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