IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

Inhibitors of apoptosis proteins (IAPs) are a highly conserved class of multifunctional proteins. Rac1 is a well-studied Rho GTPase that controls numerous basic cellular processes. While the regulation of nucleotide binding to Rac1 is well understood, the molecular mechanisms controlling Rac1 degrad...

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Detalhes bibliográficos
Main Authors: Oberoi, Tripat Kaur, Dogan, Taner, Hocking, Jennifer C, Scholz, Rolf-Peter, Mooz, Juliane, Anderson, Carrie L, Karreman, Christiaan, Meyer zu Heringdorf, Dagmar, Schmidt, Gudula, Ruonala, Mika, Namikawa, Kazuhiko, Harms, Gregory S, Carpy, Alejandro, Macek, Boris, Köster, Reinhard W, Rajalingam, Krishnaraj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252583/
https://ncbi.nlm.nih.gov/pubmed/22117219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.423
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