Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1

Mitogen-activated protein kinases (MAPKs) are highly conserved protein kinase modules, and they control fundamental cellular processes. While the activation of MAPKs has been well studied, little is known on the mechanisms driving their inactivation. Here we uncover a role for ubiquitination in the...

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Main Authors: Takeda, Armelle-Natsuo, Oberoi-Khanuja, Tripat Kaur, Glatz, Gabor, Schulenburg, Katharina, Scholz, Rolf-Peter, Carpy, Alejandro, Macek, Boris, Remenyi, Attila, Rajalingam, Krishnaraj
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195761/
https://ncbi.nlm.nih.gov/pubmed/24975362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201487808
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