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IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
Inhibitors of apoptosis proteins (IAPs) are a highly conserved class of multifunctional proteins. Rac1 is a well-studied Rho GTPase that controls numerous basic cellular processes. While the regulation of nucleotide binding to Rac1 is well understood, the molecular mechanisms controlling Rac1 degrad...
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| 主要な著者: | , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252583/ https://ncbi.nlm.nih.gov/pubmed/22117219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.423 |
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