Type I Phosphatidylinositol Phosphate Kinase Beta Regulates Focal Adhesion Disassembly by Promoting β1 Integrin Endocytosis

Cell migration requires the regulated disassembly of focal adhesions, but the underlying mechanisms remain poorly defined. We have previously shown that focal adhesion disassembly requires the dynamin 2- and clathrin-dependent endocytosis of ligand-activated β1 integrins. Here, we identify type I ph...

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Autori principali: Chao, Wei-Ting, Ashcroft, Felicity, Daquinag, Alexes C., Vadakkan, Tegy, Wei, Zhubo, Zhang, Pumin, Dickinson, Mary E., Kunz, Jeannette
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937533/
https://ncbi.nlm.nih.gov/pubmed/20624912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01207-09
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