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Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins

Cell migration requires the controlled disassembly of focal adhesions, but the underlying mechanisms remain poorly understood. Here, we show that adhesion turnover is mediated through dynamin- and clathrin-dependent endocytosis of activated β1 integrins. Consistent with this, clathrin and the clathr...

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Detalhes bibliográficos
Main Authors: Chao, Wei-Ting, Kunz, Jeannette
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801759/
https://ncbi.nlm.nih.gov/pubmed/19306879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.03.037
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