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Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins
Cell migration requires the controlled disassembly of focal adhesions, but the underlying mechanisms remain poorly understood. Here, we show that adhesion turnover is mediated through dynamin- and clathrin-dependent endocytosis of activated β1 integrins. Consistent with this, clathrin and the clathr...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801759/ https://ncbi.nlm.nih.gov/pubmed/19306879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.03.037 |
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