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Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells

Focal adhesion disassembly is regulated by microtubules (MTs) through an unknown mechanism that involves dynamin. To test whether endocytosis may be involved, we interfered with the function of clathrin or its adaptors autosomal recessive hypercholesteremia (ARH) and Dab2 (Disabled-2) and found that...

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Detalhes bibliográficos
Main Authors: Ezratty, Ellen J., Bertaux, Claire, Marcantonio, Eugene E., Gundersen, Gregg G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806590/
https://ncbi.nlm.nih.gov/pubmed/19951918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904054
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