Type I Phosphatidylinositol Phosphate Kinase Beta Regulates Focal Adhesion Disassembly by Promoting β1 Integrin Endocytosis

Cell migration requires the regulated disassembly of focal adhesions, but the underlying mechanisms remain poorly defined. We have previously shown that focal adhesion disassembly requires the dynamin 2- and clathrin-dependent endocytosis of ligand-activated β1 integrins. Here, we identify type I ph...

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Auteurs principaux: Chao, Wei-Ting, Ashcroft, Felicity, Daquinag, Alexes C., Vadakkan, Tegy, Wei, Zhubo, Zhang, Pumin, Dickinson, Mary E., Kunz, Jeannette
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937533/
https://ncbi.nlm.nih.gov/pubmed/20624912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01207-09
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