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TNF-α-Induced Mitochondrial Alterations in Human T Cells Requires FADD and Caspase-8 Activation but Not RIP and Caspase-3 Activation

Although much is known about how TNF-α induces apoptosis in the presence of inhibitors of protein synthesis, little is known about how it induces apoptosis without these inhibitors. In this report we investigated temporal sequence of events induced by TNF-α in the absence of protein synthesis. Regar...

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Bibliografiske detaljer
Main Authors: Shakibaei, Mehdi, Sung, Bokyung, Sethi, Gautam, Aggarwal, Bharat B.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935348/
https://ncbi.nlm.nih.gov/pubmed/20136500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.3036
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