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TNF-α-Induced Mitochondrial Alterations in Human T Cells Requires FADD and Caspase-8 Activation but Not RIP and Caspase-3 Activation

Although much is known about how TNF-α induces apoptosis in the presence of inhibitors of protein synthesis, little is known about how it induces apoptosis without these inhibitors. In this report we investigated temporal sequence of events induced by TNF-α in the absence of protein synthesis. Regar...

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Autors principals: Shakibaei, Mehdi, Sung, Bokyung, Sethi, Gautam, Aggarwal, Bharat B.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935348/
https://ncbi.nlm.nih.gov/pubmed/20136500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.3036
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