Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes

INTRODUCTION: Inflammatory cytokines play a key role in the pathogenesis of joint diseases such as rheumatoid arthritis (RA). Current therapies target mainly tumor necrosis factor α (TNF-α) as this has proven benefits. However, a large number of patients do not respond to or become resistant to anti...

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Bibliographic Details
Main Authors: Buhrmann, Constanze, Shayan, Parviz, Aggarwal, Bharat B, Shakibaei, Mehdi
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979010/
https://ncbi.nlm.nih.gov/pubmed/24283517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4393
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