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Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α

While Lymphotoxin α (TNF-β), a product of lymphocytes, is known to play a pivotal role in inflammatory joint environment, resveratrol has been shown to possess anti-inflammatory and chondroprotective effects via activation of the histondeacetylase Sirt1. Whether TNF-β induction of inflammatory pathw...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Buhrmann, Constanze, Popper, Bastian, Aggarwal, Bharat B., Shakibaei, Mehdi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667866/
https://ncbi.nlm.nih.gov/pubmed/29095837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186993
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