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Highly Efficient Diastereoselective Reduction of α-Fluoroimines

[Image: see text] A highly selective reduction of α-fluoroimines to the corresponding β-fluoroamines has been developed utilizing trichlorosilane as the reductant. The key aspect of this reaction is the ability of fluorine and nitrogen to activate organosilanes leading to high diastereoselectivity (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Malamakal, Roy M., Hess, Whitney R., Davis, Todd A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929650/
https://ncbi.nlm.nih.gov/pubmed/20408600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100647b
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