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Highly Efficient Diastereoselective Reduction of α-Fluoroimines

[Image: see text] A highly selective reduction of α-fluoroimines to the corresponding β-fluoroamines has been developed utilizing trichlorosilane as the reductant. The key aspect of this reaction is the ability of fluorine and nitrogen to activate organosilanes leading to high diastereoselectivity (...

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Détails bibliographiques
Auteurs principaux: Malamakal, Roy M., Hess, Whitney R., Davis, Todd A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929650/
https://ncbi.nlm.nih.gov/pubmed/20408600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100647b
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