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γ-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice
Atherosclerosis is a chronic inflammatory disease resulting from interactions between lipids, macrophages and arterial wall cells. The Notch signaling pathway is involved in the activation of macrophages in atherosclerotic lesions. This study examined whether pharmacological inhibition of Notch sign...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929363/ https://ncbi.nlm.nih.gov/pubmed/19345673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.154 |
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