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Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice

Macrophage polarization and inflammation are key factors for the onset and progression of atherosclerosis. The immunoproteasome complex consists of three inducible catalytic subunits (LMP2, LMP10, and LMP7) that play a critical role in the regulation of these risk factors. We recently demonstrated t...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Liao, Jiawei, An, Xiangbo, Yang, Xiaolei, Lin, Qiu-Yue, Liu, Shuang, Xie, Yunpeng, Bai, Jie, Xia, Yun-Long, Li, Hui-Hua
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644912/
https://ncbi.nlm.nih.gov/pubmed/33195259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.592048
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