γ-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice

Atherosclerosis is a chronic inflammatory disease resulting from interactions between lipids, macrophages and arterial wall cells. The Notch signaling pathway is involved in the activation of macrophages in atherosclerotic lesions. This study examined whether pharmacological inhibition of Notch sign...

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Detaylı Bibliyografya
Asıl Yazarlar: Aoyama, Toru, Takeshita, Kyosuke, Kikuchi, Ryosuke, Yamamoto, Koji, Cheng, Xian Wu, Liao, James K., Murohara, Toyoaki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929363/
https://ncbi.nlm.nih.gov/pubmed/19345673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.154
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