Loading...

Liver-selective γ-secretase inhibition ameliorates diet-induced hepatic steatosis, dyslipidemia and atherosclerosis

Hepatic γ-secretase regulates low-density lipoprotein receptor (LDLR) cleavage and degradation, affecting clearance of plasma triglyceride (TG)-rich lipoproteins (TRLs). In this study, we investigated whether γ-secretase inhibition modulates risk of Western (high-fat/sucrose and high-cholesterol)-ty...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Biochem Biophys Res Commun
Main Authors: Kim, KyeongJin, Yu, Junjie, Kang, Jin Ku, Morrow, John P., Pajvani, Utpal B.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308114/
https://ncbi.nlm.nih.gov/pubmed/32439159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.04.157
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!