Differential p53-independent Outcomes of p19Arf Loss in Oncogenesis

One reported function of the tumor suppressor p19(Arf) is to stabilize p53, providing a critical checkpoint in the response to oncogenic insults. Acute loss of Pten leads to an increase in the abundance of p19(Arf), p53, and p21 proteins as part of a fail-safe senescence response. Here, we report th...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Chen, Zhenbang, Carracedo, Arkaitz, Lin, Hui-Kuan, Koutcher, Jason A., Behrendt, Nille, Egia, Ainara, Alimonti, Andrea, Carver, Brett S., Gerald, William, Teruya-Feldstein, Julie, Loda, Massimo, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928478/
https://ncbi.nlm.nih.gov/pubmed/19690330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000053
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares