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Polymorphisms and Disease: Hotspots of Inactivation in Methyltransferases

Methyltransferases catalyze methylation processes essential for protein/DNA repair, transcriptional regulation, and drug metabolism in vivo. More than 500 human methyltransferase polymorphisms have been identified, many of which are linked to disease. We mapped all available coding polymorphisms of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rutherford, Karen, Daggett, Valerie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928399/
https://ncbi.nlm.nih.gov/pubmed/20382027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.03.007
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