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Polymorphisms and Disease: Hotspots of Inactivation in Methyltransferases

Methyltransferases catalyze methylation processes essential for protein/DNA repair, transcriptional regulation, and drug metabolism in vivo. More than 500 human methyltransferase polymorphisms have been identified, many of which are linked to disease. We mapped all available coding polymorphisms of...

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Detalhes bibliográficos
Main Authors: Rutherford, Karen, Daggett, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928399/
https://ncbi.nlm.nih.gov/pubmed/20382027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.03.007
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