A carregar...
Four Human Thiopurine S-Methyltransferase Alleles Severely Affect Protein Structure and Dynamics
Thiopurine S-methyltransferase (TPMT) metabolizes cytotoxic thiopurine drugs used in the treatment of leukemia and inflammatory bowel disease. TPMT is a major pharmacogenomic target with 23 alleles identified to date. Several of these alleles cause rapid protein degradation and/or aggregation, makin...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518407/ https://ncbi.nlm.nih.gov/pubmed/18482735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.032 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|