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Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease

AIM: To evaluate the relationship between thiopurine S-methyltransferase (TPMT) polymorphisms and thiopurine-induced adverse drug reactions (ADRs) in inflammatory bowel disease (IBD). METHODS: Eligible articles that compared the frequency of TPMT polymorphisms among thiopurine-tolerant and -intolera...

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Autori principali: Dong, Xian-Wen, Zheng, Qing, Zhu, Ming-Ming, Tong, Jing-Lu, Ran, Zhi-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: The WJG Press and Baishideng 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896757/
https://ncbi.nlm.nih.gov/pubmed/20593505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i25.3187
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