Thiopurine S-methyltransferase genetic polymorphisms in adult patients with inflammatory bowel diseases in the Latvian population

BACKGROUND: Thiopurine methyltransferase (TPMT) plays a significant role in the metabolism of thiopurines, and, for patients with inflammatory bowel disease (IBD), it is useful to perform TPMT genotyping prior to azathioprine (AZA) treatment. In this study, we determined TPMT gene polymorphisms in a...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: Zalizko, Polina, Stefanovics, Juris, Sokolovska, Jelizaveta, Paramonova, Natalia, Klavina, Evija, Erts, Renars, Rovite, Vita, Klovins, Janis, Pukitis, Aldis
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361485/
https://ncbi.nlm.nih.gov/pubmed/32704308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284820937426
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