Thiopurine S-methyltransferase genetic polymorphisms in adult patients with inflammatory bowel diseases in the Latvian population

BACKGROUND: Thiopurine methyltransferase (TPMT) plays a significant role in the metabolism of thiopurines, and, for patients with inflammatory bowel disease (IBD), it is useful to perform TPMT genotyping prior to azathioprine (AZA) treatment. In this study, we determined TPMT gene polymorphisms in a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Therap Adv Gastroenterol
Main Authors: Zalizko, Polina, Stefanovics, Juris, Sokolovska, Jelizaveta, Paramonova, Natalia, Klavina, Evija, Erts, Renars, Rovite, Vita, Klovins, Janis, Pukitis, Aldis
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361485/
https://ncbi.nlm.nih.gov/pubmed/32704308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284820937426
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