Thiopurine S-methyltransferase genetic polymorphisms in adult patients with inflammatory bowel diseases in the Latvian population

BACKGROUND: Thiopurine methyltransferase (TPMT) plays a significant role in the metabolism of thiopurines, and, for patients with inflammatory bowel disease (IBD), it is useful to perform TPMT genotyping prior to azathioprine (AZA) treatment. In this study, we determined TPMT gene polymorphisms in a...

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Dades bibliogràfiques
Publicat a:Therap Adv Gastroenterol
Autors principals: Zalizko, Polina, Stefanovics, Juris, Sokolovska, Jelizaveta, Paramonova, Natalia, Klavina, Evija, Erts, Renars, Rovite, Vita, Klovins, Janis, Pukitis, Aldis
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361485/
https://ncbi.nlm.nih.gov/pubmed/32704308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284820937426
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