Thiopurine S-methyltransferase genetic polymorphisms in adult patients with inflammatory bowel diseases in the Latvian population

BACKGROUND: Thiopurine methyltransferase (TPMT) plays a significant role in the metabolism of thiopurines, and, for patients with inflammatory bowel disease (IBD), it is useful to perform TPMT genotyping prior to azathioprine (AZA) treatment. In this study, we determined TPMT gene polymorphisms in a...

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Dettagli Bibliografici
Pubblicato in:Therap Adv Gastroenterol
Autori principali: Zalizko, Polina, Stefanovics, Juris, Sokolovska, Jelizaveta, Paramonova, Natalia, Klavina, Evija, Erts, Renars, Rovite, Vita, Klovins, Janis, Pukitis, Aldis
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361485/
https://ncbi.nlm.nih.gov/pubmed/32704308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284820937426
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