Thiopurine-methyltransferase variants in inflammatory bowel disease: Prevalence and toxicity in Brazilian patients

AIM: To analyze the prevalence of thiopurine-methyltransferase (TPMT) genotypes and their association with drug toxicity in inflammatory bowel disease (IBD) patients from southeastern Brazil. METHODS: A total of 219 consecutive patients with IBD, of which 146 had Crohn’s disease and 73 had ulcerativ...

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Hlavní autoři: Carvalho, Ana Teresa P, Esberard, Barbara C, Fróes, Renata S B, Rapozo, Davy C M, Grinman, Ana B, Simão, Tatiana A, Santos, Juliana C V C, Carneiro, Antonio José V, Ribeiro-Pinto, Luis Felipe, de Souza, Heitor S P
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2014
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Brief Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964403/
https://ncbi.nlm.nih.gov/pubmed/24696613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i12.3327
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