Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

BACKGROUND—Measurement of 6-thioguanine nucleotide concentrations may be useful for optimising treatment with azathioprine and 6-mercaptopurine.
METHODS—We conducted a study of 170 patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine to determine the relationship be...

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Detalhes bibliográficos
Main Authors: Lowry, P, Franklin, C, Weaver, A, Pike, M, Mays, D, Tremaine, W, Lipsky, J, Sandborn, W
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728511/
https://ncbi.nlm.nih.gov/pubmed/11600469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.49.5.665
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