טוען...
In Vivo RNAi-Mediated α-Synuclein Silencing Induces Nigrostriatal Degeneration
Two small-interfering RNAs (siRNAs) targeting α-synuclein (α-syn) and three control siRNAs were cloned in an adeno-associated virus (AAV) vector and unilaterally injected into rat substantia nigra pars compacta (SNc). Reduction of α-syn resulted in a rapid (4 week) reduction in the number of tyrosin...
שמור ב:
| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927065/ https://ncbi.nlm.nih.gov/pubmed/20551914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.115 |
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