Distinct Changes in cAMP and Extracellular Signal-Regulated Protein Kinase Signalling in L-DOPA-Induced Dyskinesia

BACKGROUND: In rodents, the development of dyskinesia produced by L-DOPA in the dopamine-depleted striatum occurs in response to increased dopamine D1 receptor-mediated activation of the cAMP - protein kinase A and of the Ras-extracellular signal-regulated kinase (ERK) signalling pathways. However,...

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Main Authors: Santini, Emanuela, Sgambato-Faure, Veronique, Li, Qin, Savasta, Marc, Dovero, Sandra, Fisone, Gilberto, Bezard, Erwan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925943/
https://ncbi.nlm.nih.gov/pubmed/20808799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012322
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