In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

Clonal evolution and outgrowth of cellular variants with additional chromosomal abnormalities are major causes of disease progression in chronic lymphocytic leukemia (CLL). Because new DNA lesions occur during S phase, proliferating cells are at the core of this problem. In this study, we used in vi...

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Main Authors: Calissano, Carlo, Damle, Rajendra N., Hayes, Gregory, Murphy, Elizabeth J., Hellerstein, Marc K., Moreno, Carol, Sison, Cristina, Kaufman, Matthew S., Kolitz, Jonathan E., Allen, Steven L., Rai, Kanti R., Chiorazzi, Nicholas
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2009
主題:
Lymphoid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925477/
https://ncbi.nlm.nih.gov/pubmed/19789386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-219634
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